Niche (architecture), an exedra or an apse that has been reduced in size;
Niche (footballer) (b. 1985), Colombian/Spanish football (soccer) player, full name Víctor Manuel Micolta Armero
Niche (horse), a British Thoroughbred racehorse
Bassline (dance music), a type of music related to UK garage also called Niche
Developmental niche, a concept for understanding the cultural context of child development
Ecological niche, a term describing the relational position of an organism's species
Niche market, a focused, targetable portion (subset) of a market sector.
Niche blogging, a blog focused on a niche market (above)
Nurses Improving Care for Healthsystem Elders, a program of the Hartford Institute for Geriatric Nursing at New York University College of Nursing
Niche cell, specific anatomic locations that regulate how stem-cell populations participate in tissue generation, maintenance and repair
Stem cell niche, the microenvironment in which stem cells are found